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    Cleve Clin J Med. 2006 Mar;73(3):251-6.

    The yin and yang of tumor necrosis factor inhibitors.

    Source

    Section of Clinical Immunology, Department of Rheumatic and Immunologic Disease, The Cleveland Clinic Foundation, OH 44195, USA. calabrl@ccf.org

    Abstract

    Tumor necrosis factor (TNF) inhibitors have proven highly effective against a number of autoimmune diseases but have been disappointing in treating others. An increase in the risk of Mycobacterium tuberculosis and other opportunistic infections has been noted in patients treated with these agents. If we use these drugs, we need to weigh their beneficial and adverse effects.

    PMID:
    16548447
    [PubMed - indexed for MEDLINE]
    Free full text

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