Display Settings:

Format

Send to:

Choose Destination
Opt Lett. 2006 Mar 15;31(6):829-31.

Fast, flexible algorithm for calculating photon correlations.

Author information

  • 1Physical Biosciences Institute, Chemistry and Materials Science Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, USA. laurence2@llnl.gov

Abstract

We introduce a new algorithm for computing correlations of photon arrival time data acquired in single-molecule fluorescence spectroscopy and fluorescence correlation spectroscopy (FCS). The algorithm is based on rewriting the correlation as a counting operation on photon pairs and can be used with arbitrary bin widths and spacing. The flexibility of the algorithm is demonstrated by use of FCS simulations and single-molecule photon antibunching experiments. Execution speed is comparable to the commonly used multiple-tau correlation technique. Wide bin spacings are possible that allow for real-time software calculation of correlations, even for high count rates.

PMID:
16544638
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Optical Society of America
    Loading ...
    Write to the Help Desk