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Curr Opin Cell Biol. 1991 Jun;3(3):474-83.

Phosphorylation of transcriptional factors and cell-cycle-dependent proteins by casein kinase II.

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  • 1Program in Molecular Medicine, University of Massachusetts Medical School, Worcester 10605.


Casein kinase II is involved in the phosphorylation of several proto-oncogenes, anti-oncogenes, and oncogenes that are nuclear transcriptional regulatory factors. The potential functions of the phosphorylations in each of these proteins are evaluated. New findings indicate that casein kinase II is a critical component of the mechanisms regulating the cell cycle.

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