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Actas Dermosifiliogr. 2006 Jan-Feb;97(1):48-51.

[Treatment of severe refractory pemphigus vulgaris with rituximab].

[Article in Spanish]

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  • 1Servicio de Dermatología, Hospital General Universitario de Valencia, Spain. gerardpitarch@hotmail.com


Pemphigus vulgaris is a potentially fatal autoimmune bullous disease. High doses of immunosuppressive drugs are used in managing severe cases of pemphigus. Rituximab, an anti-CD20 monoclonal antibody, has proven to be effective in patients with refractory pemphigus vulgaris and pemphigus foliaceus. We review cases of pemphigus vulgaris and pemphigus foliaceus not associated with lymphoma that were treated with rituximab, and we report a new case of severe refractory pemphigus vulgaris successfully treated with rituximab.

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  • [Pemphigus vulgaris treated with rituximab]. [Actas Dermosifiliogr. 2006]
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