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Neurology. 2006 Mar 14;66(5):768-70.

Thrombolytic therapy of acute ischemic stroke during pregnancy.

Author information

  • 1Stroke Program, Department of Neurology, Wayne State University, School of Medicine, Detroit, MI, USA.

Abstract

The authors report eight pregnant women with acute ischemic stroke treated with thrombolysis (rt-PA [recombinant human tissue plasminogen activator] or urokinase). Seven women recovered. Two extracranial and two asymptomatic intracranial hemorrhages complicated treatment; one woman died of arterial dissection complicating angiography. Three patients had therapeutic abortions, two fetuses were miscarried, and two babies were delivered healthy. Although pregnant women may be treated safely with thrombolytics, risks and benefits to mother and fetus must be carefully weighed.

PMID:
16534124
[PubMed - indexed for MEDLINE]
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