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1: Neurology. 2006 Mar 14;66(5):765-7.Click here to read Links
Comment in:
Neurology. 2006 Sep 12;67(5):919-20; author reply 919-20.

Different degrees of right-to-left shunting predict migraine and stroke: data from 420 patients.

Anzola GP, Morandi E, Casilli F, Onorato E.

ervizio di Neurologia, Ospedale S. Orsola FBF, Associazione Fatebenefratelli per la Ricerca (AFaR), Brescia, Italy. gpanzola@numerica.it

The authors analyzed the extent of right-to-left shunting in patients with migraine, patients with cryptogenic stroke, and controls. Patients with both migraine and stroke had larger shunts than did patients with migraine without stroke (p = 0.038), patients with no migraine with stroke (p = 0.007), and control patients (p < 0.0001). Patients with migraine have overall larger shunts than nonmigraineurs, particularly if they have had a stroke. Right-to-left shunting may be causally related to migraine and to the increased stroke risk of migraine.

PMID: 16534123 [PubMed - indexed for MEDLINE]