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J Dent. 2006 Nov;34(10):747-50. Epub 2006 Mar 13.

The effect of clove and benzocaine versus placebo as topical anesthetics.

Author information

  • 1Faculty of Dentistry, Kuwait University, Kuwait. Athbi@hsc.edu.kw

Abstract

OBJECTIVES:

The purpose of this study was to examine whether the natural herb clove can replace benzocaine as a topical anesthetic.

METHODS:

Topical agents were applied to the maxillary canine buccal mucosa of 73 adult volunteers. Four substances were tested in the study: (1) homemade clove gel, (2) benzocaine 20% gel, (3) placebo that resembles clove and (4) a placebo that resembled benzocaine. After 5 min of material application in a randomized, subject-blinded manner, each participant received two needle sticks. Pain response was registered using a 100 mm visual analogue pain scale.

RESULTS:

Both clove and benzocaine gels had significantly lower mean pain scores than placebos (p=0.005). No significant difference was observed between clove and benzocaine regarding pain scores.

CONCLUSION:

Clove gel might possess a potential to replace benzocaine as a topical agent before needle insertion.

PMID:
16530911
[PubMed - indexed for MEDLINE]
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