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1: Clin Rheumatol. 2006 Jul;25(4):542-3. Epub 2006 Mar 7.Click here to read Links

Anti-topoisomerase I antibodies in systemic lupus erythematosus as a marker of severe nephritis.

Hamidou MA, Audrain MA, Masseau A, Agard C, Moreau A.

Department of Internal Medicine, University Hospital Hôtel-Dieu, Place Alexis Ricordeau, 44 035, Nantes, France. mohamed.hamidou@chu-nantes.fr

The authors report nine patients with systemic lupus erythematosus associated with anti-topoisomerase I antibodies (ELISA test) without features of systemic sclerosis. These antibodies were correlated with the disease activity and might be a marker of the severity of the closely related to difusse proliferative glomerulonephritis.

PMID: 16525896 [PubMed - indexed for MEDLINE]