Your browser version may not work well with NCBI's Web applications. More information here...
1: Zhonghua Zhong Liu Za Zhi. 1991 Mar;13(2):120-2.Links

[Pharmakinetics of carboplatin in cancer patients]

[Article in Chinese]

Zhang M.

Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.

Pharmakinetics of carboplatin was studied in 6 cancer patients who received carboplatin (300 mg/m2) by 30 minute intravenous infusion. Platinum plasma concentration was measured by reverse high performance liquid chromatography. The results showed that total platinum plasma clearance was biphasic in all patients with a short initial phase half-life of 1.27 hrs and a long second phase half-life of 6.92 hrs. The distribution volume of the drug was 57.78 L/m2 and area under the total platinum concentration curves was 84.71 mg/L.hr.

PMID: 1652416 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Carboplatin (Paraplatin® )

    Your doctor has ordered the drug carboplatin to help treat your illness. The drug is given by injection into a vein.

  • Source: AHFS Consumer Medication Information