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Int J Sport Nutr Exerc Metab. 2005 Dec;15(6):653-64.

Effects of ribose supplementation prior to and during intense exercise on anaerobic capacity and metabolic markers.

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  • 1Exercise and Sport Nutrition Laboratory, Center for Exercise, Nutrition and Preventive Health Research, Dept of Health, Human Performance and Recreation, Baylor University, Waco, TX 76798-7313, USA.


This study examined whether ribose supplementation before and during intense anaerobic exercise impacts anaerobic capacity and metabolic markers. Twelve moderately trained male cyclists (22.3 +/- 2.2 y; 181 +/- 6 cm, 74.8 +/- 9 kg) participated in the study. Subjects were familiarized and fasted for 8 h after standardizing nutritional intake. In a double blind and crossover manner subjects ingested either a 150 mL placebo or ribose (3 g ribose + 150 microg folate). Subjects rested for 25 min and completed 5 x 30 s anaerobic capacity tests with 3 min passive rest. Six capillary blood samples were taken prior to and after sprints for adenine nucleotide breakdown determination. The experiment was repeated 1 wk later with alternative drink. Data were analyzed by repeated measures ANOVA. No significant interactions were observed for any performance or blood variables. D-ribose supplementation has no impact on anaerobic exercise capacity and metabolic markers after high-intensity cycling exercise.

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