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Prog Neuropsychopharmacol Biol Psychiatry. 2006 Jul;30(5):865-72. Epub 2006 Mar 7.

The hyper-systemizing, assortative mating theory of autism.

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  • 1Autism Research Centre, Department of Psychiatry, University of Cambridge, Douglas House, 18b Trumpington Road, Cambridge, CB2 2AH, UK.


The hyper-systemizing theory of autism proposes that the systemizing mechanism is set too high in people with autism. As a result, they can only cope with highly lawful systems, and cannot cope with systems of high variance or change (such as the social world of other minds). They appear 'change-resistant'. This proposal extends the extreme male brain theory of autism. Finally, evidence is reviewed for autism being the genetic result of assortative mating of two high systemizers.

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