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J Clin Microbiol. 2006 Mar;44(3):1094-7.

Sensitive line probe assay that simultaneously detects mutations conveying resistance to lamivudine and adefovir.

Author information

  • 1Division of Gastroenterology, University of Michigan Medical Center, 1500 East Medical Center Drive, 3912 Taubman Center, Box 0362, Ann Arbor, Michigan 48109-0362, USA.

Abstract

The INNO-LiPA HBV DR v2 assay is designed to detect hepatitis B virus mutations conveying resistance to lamivudine and adefovir. Our study confirms that this assay can simultaneously detect the presence of lamivudine and adefovir resistance mutations in clinical samples, has a high degree of concordance with sequencing, and can detect mutants earlier.

PMID:
16517902
[PubMed - indexed for MEDLINE]
PMCID:
PMC1393162
Free PMC Article
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