Biochem Int. 1991 Mar;23(4):723-31.

Quantitation of Mr 46000 and Mr 300000 mannose 6-phosphate receptors in human cells and tissues.

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Georg-August-University, Göttingen, Germany.

Abstract

A highly specific enzyme-linked immunosorbent assay for quantitation of the Mr 46000 Da and Mr 300000 Da mannose 6-phosphate receptors was developed. The assay allows to detect ng amounts of human mannose 6-phosphate receptors. Analysis of human cells and tissues revealed significant differences in their contents of the two mannose 6-phosphate receptors, normalized for total cell protein. The ratio of the two mannose 6-phosphate receptors also differed among cells and tissues, suggesting that their steady state concentrations are regulated independently.

PMID:: 1651728; [PubMed - indexed for MEDLINE]

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Quantitation of Mr 46000 and Mr 300000 mannose 6-phosphate receptors in human cells and tissues.

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