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1: Genome Biol. 2006;7(1):102. Epub 2006 Feb 1.Click here to read Click here to read Links

On the evolution of the standard amino-acid alphabet.

Lu Y, Freeland S.

Department of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA.

Although one standard amino-acid 'alphabet' is used by most organisms on Earth, the evolutionary cause(s) and significance of this alphabet remain elusive. Fresh insights into the origin of the alphabet are now emerging from disciplines as diverse as astrobiology, biochemical engineering and bioinformatics.

PMID: 16515719 [PubMed - indexed for MEDLINE]

PMCID: PMC1431706