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    J Bone Joint Surg Br. 2006 Mar;88(3):396-9.

    Multiple skeletal metastases from a giant cell tumour of the distal fibula with fatal outcome.

    Source

    Orthopaedic Department, Tübingen University Hospital, Hoppe-Seyler-Str. 3, D-72076 Tübingen, Germany.

    Abstract

    A giant cell tumour is a primary lesion of bone of intermediate severity. Its histogenesis is unclear. In a few cases pulmonary metastases have been described. Multiple skeletal metastases in the absence of sarcomatous change have been observed. We present a case report of a 25-year-old woman with a recurrent giant cell tumour of the distal fibula. After a second recurrence and six years after the initial diagnosis, she rapidly developed multiple bony metastases. The outcome was fatal.

    PMID:
    16498021
    [PubMed - indexed for MEDLINE]
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