Age Ageing. 2006 Mar;35(2):200-1.

Metformin-related vitamin B12 deficiency.

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Medical and Geriatric Unit, Shatin Hospital, New Territories, Hong Kong, China. kwliuhk@yahoo.com

Abstract

Metformin is an invaluable hypoglycaemic agent. We report two cases who had symptomatic vitamin B12 deficiency related to metformin use; the mechanisms are discussed. The clinician must be aware of the possibility of metformin-associated B12 deficiency in users who suffer cognitive impairment, peripheral neuropathy, subacute combined degeneration of the cord or anaemia.

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Metformin and vitamin B12 deficiency: the role of H2 receptor antagonists and proton pump inhibitors. [Age Ageing. 2007]
Metformin and vitamin B12 deficiency: the role of H2 receptor antagonists and proton pump inhibitors.Varughese GI, Scarpello JH. Age Ageing. 2007 Jan; 36(1):110-1; discussion 111.

PMID:: 16495296; [PubMed - indexed for MEDLINE]

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Age Ageing. 2006 Mar ;35(2):200-1.

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