Acute effects of C-peptide on gastric emptying in longstanding type 1 diabetes

Julie E Stevens; Antonietta Russo; Carol A Delaney; Peter J Collins; Michael Horowitz; Karen L Jones

doi:10.1007/s10286-006-0308-9

Acute effects of C-peptide on gastric emptying in longstanding type 1 diabetes

Clin Auton Res. 2006 Feb;16(1):55-7. doi: 10.1007/s10286-006-0308-9.

Authors

Julie E Stevens¹, Antonietta Russo, Carol A Delaney, Peter J Collins, Michael Horowitz, Karen L Jones

Affiliation

¹ Dept. of Medicine, University of Adelaide, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia.

PMID: 16477496
DOI: 10.1007/s10286-006-0308-9

Abstract

Gastric emptying (GE) of a solid (100 g beef) and liquid (150 ml 10 % dextrose) meal was measured in eight patients with type 1 diabetes during intravenous infusion of C-peptide (6 pmol/kg/ min) or isotonic saline. C-peptide had no effect on either solid or liquid GE.

Publication types

Randomized Controlled Trial
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Blood Glucose / analysis
C-Peptide / blood
C-Peptide / pharmacology*
Diabetes Mellitus, Type 1 / blood
Diabetes Mellitus, Type 1 / physiopathology*
Female
Gastric Emptying / drug effects*
Gastric Emptying / physiology
Humans
Male
Middle Aged
Time Factors

Substances

Blood Glucose
C-Peptide