Vet Immunol Immunopathol. 2006 May 15;111(1-2):31-40. Epub 2006 Feb 10.

Immune escape of equine herpesvirus 1 and other herpesviruses of veterinary importance.

van der Meulen KM, Favoreel HW, Pensaert MB, Nauwynck HJ.

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Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium. karen.vandermeulen@ugent.be

Abstract

Equine herpesvirus (EHV)-1 is a pathogen of horses, well known for its ability to induce abortion and nervous system disorders. Clinical signs may occur despite the presence of a virus-specific immune response in the horse. The current review will summarize the research, on how, EHV-1-infected cells can hide from recognition by the immune system. Research findings on immune evasion of EHV-1 will be compared with those of other herpesviruses of veterinary importance.

PMID:: 16472872; [PubMed - indexed for MEDLINE]

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