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Kidney Int. 2006 Feb;69(4):723-9.
Fifty years of Balkan endemic nephropathy: daunting questions, elusive answers.
Section of Nephrology, Tulane University Medical School, New Orleans, Louisiana 70112, USA. vbatuma@tulane.edu
Balkan endemic nephropathy (BEN) has remained a geographically constant endemic for 50 years. Despite extensive research, its etiology remains unknown. In the current issue, in a study in one of the earliest sites where the endemic was first recognized, Dimitrov et al. confirm the persistance of the endemic into a new generation and also identify a maternal link in the pathogenesis of BEN. This intriguing finding needs to be confirmed in other endemic areas.
PMID: 16467889 [PubMed - indexed for MEDLINE]