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    J Fam Pract. 2006 Feb;55(2):106-12.

    Cephalosporins can be prescribed safely for penicillin-allergic patients.

    Pichichero ME.

    University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA. Michael_pichichero@urmc.rochester.edu

    The widely quoted cross-allergy risk of 10% between penicillin and cephalosporins is a myth. Cephalothin, cephalexin, cefadroxil, and cefazolin confer an increased risk of allergic reaction among patients with penicillin allergy. Cefprozil, cefuroxime, cefpodoxime, ceftazidime, and ceftriaxone do not increase risk of an allergic reaction.

    PMID: 16451776 [PubMed - indexed for MEDLINE]

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