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Physiology (Bethesda). 2006 Feb;21:69-78.

Calcium-activated potassium channels and the regulation of vascular tone.

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  • 1Department of Pharmacology, College of Medicine, University of Vermont, Burlington, Vermont, USA.


Different calcium signals in the endothelium and smooth muscle target different types of Ca2+-sensitive K+ channels to modulate vascular function. These differential calcium signals and targets represent multilayered opportunities for prevention and/or treatment of vascular dysfunctions.

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