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J Endocrinol. 2005 Dec;187(3):327-32.

MicroRNAs and endocrine biology.

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  • 1UCSF Diabetes Center, Department of Microbiology and Immunology, University of California, San Francisco, California 94122-0534, USA.


microRNAs (miRNAs) are highly conserved, non-coding RNAs that powerfully regulate gene expression at the post-transcriptional level. These fascinating molecules play essential roles in many biological processes in mammals, including insulin secretion, B-cell development, and adipocyte differentiation. This review provides a general background regarding current knowledge about miRNA biogenesis and the potential contributions of these RNAs to endocrine function.

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