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    Genome Biol. 2005;6(13):244. Epub 2006 Jan 3.

    Recent developments in membrane-protein structural genomics.

    Gao FP, Cross TA.

    Department of Chemistry and Biochemistry, and the National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL 32310, USA. gao@magnet.fsu.edu

    Recent work has identified the topology of almost all the inner membrane proteins in Escherichia coli, and advances in nuclear magnetic resonance spectroscopy now allow the determination of alpha-helical membrane protein structures at high resolution. Together these developments will help overcome the current limitations of high-throughput determination of membrane protein structures.

    PMID: 16420681 [PubMed - indexed for MEDLINE]

    PMCID: 1414099

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