Send to:

Choose Destination
See comment in PubMed Commons below
Comp Biochem Physiol B Biochem Mol Biol. 2006 Mar;143(3):330-4. Epub 2006 Jan 18.

Arginine vasotocin (AVT) and isotocin (IT) in fish brain: diurnal and seasonal variations.

Author information

  • 1Department of Genetics and Marine Biotechnology, Institute of Oceanology of Polish Academy of Sciences, sw. Wojciecha 5 Str., 81-347 Gdynia, Poland.


An HPLC assay with solid-phase extraction and fluorescence derivatization was developed for measurement of arginine vasotocin (AVT) and isotocin (IT) in the neural tissues of fish. The efficiency and usefulness of the method have been verified in experiments by examination of peptides concentrations in brains of three fish species. The day-night changes in neuropeptides levels have been studied in brains of adult sea bream (Sparus aurata) and juvenile Atlantic salmon (Salmo salar). Seasonal fluctuations have been investigated in brains of three-spined sticklebacks (Gasterosteus aculeatus). The AVT and IT biosynthesis in brain seems to be controlled independently and probably each neuropeptide plays a different role in a circadian time-keeping system and an endocrine calendar in fish.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk