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Zhonghua Nei Ke Za Zhi. 2005 Dec;44(12):902-5.

[The differential features of bone marrow morphology of several rare infectious disorders].

[Article in Chinese]

Author information

  • 1Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.



To facilitate the diagnosis of histoplasmosis, kala-azar, penicilliosis marneffei, toxoplasmosis and cryptococcosis with the help of bone marrow morphology.


The clinical features and bone marrow cytomorphology in 7 cases of histoplasmosis, 1 case of kela-azar, 1 case of penicilliosis marneffei, 2 cases of toxoplasmosis and 3 cases of cryptococcosis were studied.


In the bone marrow examination, the form of histoplasma capsule was ovoid with a colorless circle. The morphology of Leishmania donovani was similar to that of histoplasma capsule except that there were terkinetoplasts present in the former. Sausage form and central cross wall were signs of Penicillium marneffei. Toxoplasma gondii looked like a banana and cryptococcus neoformans was larger than the others and had a thick capsule.


The examination of bone marrow is important to the diagnosis of these rare infectious diseases.

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