Thyroid cancer review 3: management of medullary and undifferentiated thyroid cancer.
Department of Otolaryngology, Head and Neck Surgery, York Hospital, York, UK.
This is the last of the three review articles dealing with thyroid cancer. Over 90% of thyroid cancer is of the differentiated type associated with a very good 10-year disease-free survival rate. In contrast, the rare forms of thyroid cancer which comprise medullary thyroid cancer arising from parafollicluar C cells, Hurthle cell carcinoma, anaplastic carcinoma, thyroid lymphoma and squamous cell carcinoma are typically associated with a poorer survival rate. Management is based upon small retrospective cohort studies.
PMID: 16409432 [PubMed - indexed for MEDLINE]