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    Australas J Dermatol. 2006 Feb;47(1):57-9.

    Pravastatin-induced lichenoid drug eruption.

    Source

    Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

    Abstract

    SUMMARY A 64-year-old woman presented with diffuse and numerous pigmented macules on her face and upper back. Histopathological examination of a skin punch biopsy of the rash showed a lichenoid dermatitis. The most likely offending drug was pravastatin. Cessation of pravastatin resulted in gradual fading of the pigmentation. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors have previously been reported to cause lichenoid drug eruptions.

    PMID:
    16405486
    [PubMed - indexed for MEDLINE]

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