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Curr Biol. 2006 Jan 10;16(1):R18-20.

Nebulin: does it measure up as a ruler?

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  • 1Department of Cell Biology- CB163, The Scripps Research Institute, La Jolla, CA 92037, USA.


A recent study has shown that the giant protein nebulin maintains the lengths of actin filaments in striated muscle cells. Although on the surface, nebulin looks like a molecular ruler, it may be playing a more complex role in regulating dynamics at the pointed end of actin filaments in striated muscle.

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