Format

Send to

Choose Destination
See comment in PubMed Commons below
Indian J Pediatr. 2005 Nov;72(11):935-8.

Efficacy of tyndalized Lactobacillus acidophilus in acute diarrhea.

Author information

  • 1Department of Pediatrics, JN Medical College, Aligarh Muslim University, Aligarh, India.

Abstract

OBJECTIVE:

A double-blind randomized controlled-trial was done to evaluate the efficacy of tyndalized Lactobacillus acidophilus in acute diarrhea.

METHODS:

All children from 6 months to 12 years with acute diarrhea were included. Lactobacillus acidophilus/placebo was given to the children for 3 days with ORS and feeds. Intake-output was recorded 4 hourly. Of the 98 children, 48 received lactobacillus and 50 the placebo.

RESULTS:

ORS consumed, frequency of stools, duration of diarrhea, time for rehydration, hospital stay, weight gain and IVF needed were comparable in the two study groups. There were 4 treatment failures in the lactobacillus group and none in the placebo group (OR 0.92, 95%CI 0.84-0.99). In the rotaviral diarrhea and in those who had diarrhea of less then 60 hours the difference did not reach statistical significance.

CONCLUSION:

There is no significant benefit of tyndalized Lactobacillus acidophilus in acute diarrhea.

PMID:
16391447
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk