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Nucleic Acids Res. 2006 Jan 1;34(Database issue):D95-7.

A new generation of JASPAR, the open-access repository for transcription factor binding site profiles.

Author information

  • 1Department for Molecular Biomedical Research (DMBR), VIB-Ghent University, Technologiepark 927 B-9052, Ghent (Zwijnaarde), Belgium.

Abstract

JASPAR is the most complete open-access collection of transcription factor binding site (TFBS) matrices. In this new release, JASPAR grows into a meta-database of collections of TFBS models derived by diverse approaches. We present JASPAR CORE--an expanded version of the original, non-redundant collection of annotated, high-quality matrix-based transcription factor binding profiles, JASPAR FAM--a collection of familial TFBS models and JASPAR phyloFACTS--a set of matrices computationally derived from statistically overrepresented, evolutionarily conserved regulatory region motifs from mammalian genomes. JASPAR phyloFACTS serves as a non-redundant extension to JASPAR CORE, enhancing the overall breadth of JASPAR for promoter sequence analysis. The new release of JASPAR is available at http://jaspar.genereg.net.

PMID:
16381983
[PubMed - indexed for MEDLINE]
PMCID:
PMC1347477
Free PMC Article
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