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Nucleic Acids Res. 2006 Jan 1;34(Database issue):D411-4.

Human protein reference database--2006 update.

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  • 1Institute of Bioinformatics, International Tech Park, Bangalore 560 066, India.

Abstract

Human Protein Reference Database (HPRD) (http://www.hprd.org) was developed to serve as a comprehensive collection of protein features, post-translational modifications (PTMs) and protein-protein interactions. Since the original report, this database has increased to >20 000 proteins entries and has become the largest database for literature-derived protein-protein interactions (>30 000) and PTMs (>8000) for human proteins. We have also introduced several new features in HPRD including: (i) protein isoforms, (ii) enhanced search options, (iii) linking of pathway annotations and (iv) integration of a novel browser, GenProt Viewer (http://www.genprot.org), developed by us that allows integration of genomic and proteomic information. With the continued support and active participation by the biomedical community, we expect HPRD to become a unique source of curated information for the human proteome and spur biomedical discoveries based on integration of genomic, transcriptomic and proteomic data.

PMID:
16381900
[PubMed - indexed for MEDLINE]
PMCID:
PMC1347503
Free PMC Article

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