Curr Opin Genet Dev. 1992 Apr;2(2):221-6.

The SRF and MCM1 transcription factors.

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Imperial Cancer Research Fund, London, UK.

Abstract

The mammalian transcription factor SRF (serum-response factor) and the related Saccharomyces cerevisiae transcription factor MCM1 are the prototypes of a new class of dimeric DNA-binding proteins. Their function is regulated in part by the interactions of their DNA-binding domains with accessory proteins. Recent work has advanced the functional characterization of the contributions of SRF and MCM1, and their accessory proteins to transcriptional activation.

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Review Isolation and characterization of SRF accessory proteins.
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The SRF and MCM1 transcription factors.

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