[Study on the effect of promoting intelligence development and preventing hypoxia/reoxygenation injury of selenium-banqiao-Codonopsis pilosula-overground part in mice]

Zhong Yao Cai. 2005 Aug;28(8):688-90.
[Article in Chinese]

Abstract

Objective: To study on the effect of promoting intelligence development and preventing Hypoxia/Reoxygenation injury of Selenium-Banqiao-Codonopsis pilosula-overground part in mice.

Methods: Promoting Intelligence Development experiment was induced by PIA; Hypoxia/reoxygenation ingury model was established to observe the activity of ROS, SOD, MOD and CAT in blood.

Results: Selenium-Banqiao-Codonopsis pilosula-overground part could enhance the learning and memory ability of old mice and obviously extend the swimming time of mice. It could also decrease the quality of ROS and MDA, increase the activity of SOD, but no significant effect on CAT.

Conclusion: Selenium-Banqiao-Codonopsis pilosula-overground part has effect on promoting intelligence development and preventing hypoxia/reoxygenation injury.

MeSH terms

  • Animals
  • Codonopsis / chemistry*
  • Drugs, Chinese Herbal / administration & dosage
  • Drugs, Chinese Herbal / pharmacology*
  • Hypoxia / metabolism
  • Hypoxia / pathology*
  • Intelligence
  • Learning / drug effects
  • Memory / drug effects
  • Memory Disorders / chemically induced
  • Memory Disorders / drug therapy
  • Memory Disorders / pathology*
  • Mice
  • Plant Stems / chemistry
  • Plants, Medicinal / chemistry
  • Reperfusion Injury / metabolism
  • Reperfusion Injury / pathology
  • Selenium

Substances

  • Drugs, Chinese Herbal
  • Selenium