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Expert Rev Cardiovasc Ther. 2006 Jan;4(1):119-30.

Chagas cardiomyopathy and ischemic stroke.

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  • 1Neurology Department, Sarah Hospital, SMHS, CEP 7330-150, Brasilia DF, Brazil.


American trypanosomiasis, known as Chagas disease is a major cause of cardiomyopathy in South America. Irreversible damage to the heart can appear 10-20 years after chagasic infection. The relationship between Chagas cardiomyopathy and ischemic stroke has been reviewed. Significant variables that predict ischemic stroke in chagasic patients have been identified: apical aneurysm, cardiac insufficiency, electrocardiogram arrhythmia and female gender. Chagasic cardiomyopathy should be included in the differential diagnosis of the etiology of stroke, being a potential source of cardioembolic stroke.

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