Your browser version may not work well with NCBI's Web applications. More information here...
1: Cardiol Rev. 2006 Jan-Feb;14(1):50-2. Links

Acute coronary syndrome after infliximab infusion.

Abedin M, Scheurich D, Reimold SC, Reimold AM.

Cardiology Division, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8884, USA.

The TNFalpha inhibitor infliximab is widely used in the treatment of rheumatoid arthritis and Crohn disease. Mild infusion reactions consisting of low-grade fever, headache, nausea, and fatigue are common, but we describe for the first time the occurrence of an acute coronary syndrome during infliximab administration. This case alerts infusion centers to consider the possibility that chest pain and dyspnea during infliximab infusion can represent a myocardial infarction, even in younger patients without a history of cardiac disease.

PMID: 16371767 [PubMed - indexed for MEDLINE]

Patient Drug Information