Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Mol Biol Evol. 2006 Mar;23(3):479-81. Epub 2005 Dec 20.

The contribution of LTR retrotransposon sequences to gene evolution in Mus musculus.

Abstract

Approximately 1.5% of mouse genes (Mus musculus) contain long terminal repeat retrotransposon sequences (LRS). Consistent with earlier findings in Caenorhabditis elegans, Drosophila melanogaster, and Homo sapiens, LRS are more likely to be associated with newly evolved genes. Evidence is presented that LRS are often recruited as novel exons or as spliced additions to existing exons. These novel gene configurations may be expressed initially as alternative transcripts providing an opportunity for the evolution of new gene function.

PMID:
16368779
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk