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Pediatr Nephrol. 2006 Feb;21(2):295-8. Epub 2005 Dec 17.

A case of atypical hemolytic uremic syndrome with a transient decrease in complement factor H.

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  • 1Department of Pediatrics, Eulji University School of Medicine, Daejeon, Korea. petercat67@empal.com

Abstract

We report a case of sporadic atypical hemolytic uremic syndrome (HUS) with a transient decrease in complement factor H. Referred for hemolysis and azotemia without diarrhea prodrome, this 31-month-old boy showed a decreased complement 3 (C3) and complement factor H (FH) level. However, the factor H gene (HF1) mutation was missing. After the hemolysis was controlled with plasma infusion, the C3 and FH levels recovered. The patient's renal function fully recovered and remained normal, and there was no recurrence of the HUS.

PMID:
16362720
[PubMed - indexed for MEDLINE]
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