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    Bioinformatics. 2006 Feb 15;22(4):495-6. Epub 2005 Dec 15.

    SEAN: SNP prediction and display program utilizing EST sequence clusters.

    Source

    Centre for Bioinformatics, Division of Molecular Biosciences, Imperial College London, SW7 2AZ, UK. d.huntley@imperial.ac.uk

    Abstract

    SEAN is an application that predicts single nucleotide polymorphisms (SNPs) using multiple sequence alignments produced from expressed sequence tag (EST) clusters. The algorithm uses rules of sequence identity and SNP abundance to determine the quality of the prediction. A Java viewer is provided to display the EST alignments and predicted SNPs.

    PMID:
    16357032
    [PubMed - indexed for MEDLINE]
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