Applied Genomics Inc, 525 Del Rey Avenue, Sunnyvale, CA 94085, USA. bzring@applied-genomics.com
Transplantation of human breast cancer cells into immunodeficient mice together with gene-expression microarray studies has recently identified genes implicated in the tissue tropism of breast-cancer metastasis. Such signatures of site-specific metastatic capabilities might allow the targeting of therapy to likely sites of metastasis.