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Genome Biol. 2005;6(12):241. Epub 2005 Dec 2.

Predicting the sites of metastases.

Author information

  • 1Applied Genomics Inc, 525 Del Rey Avenue, Sunnyvale, CA 94085, USA. bzring@applied-genomics.com

Abstract

Transplantation of human breast cancer cells into immunodeficient mice together with gene-expression microarray studies has recently identified genes implicated in the tissue tropism of breast-cancer metastasis. Such signatures of site-specific metastatic capabilities might allow the targeting of therapy to likely sites of metastasis.

PMID:
16356275
[PubMed - indexed for MEDLINE]
PMCID:
PMC1414081
Free PMC Article

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