Predicting the sites of metastases. [Genome Biol. 2005]

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1: Genome Biol. 2005;6(12):241. Epub 2005 Dec 2. Links

Predicting the sites of metastases.

Ring BZ, Ross DT.

Applied Genomics Inc, 525 Del Rey Avenue, Sunnyvale, CA 94085, USA. bzring@applied-genomics.com

Transplantation of human breast cancer cells into immunodeficient mice together with gene-expression microarray studies has recently identified genes implicated in the tissue tropism of breast-cancer metastasis. Such signatures of site-specific metastatic capabilities might allow the targeting of therapy to likely sites of metastasis.

PMID: 16356275 [PubMed - indexed for MEDLINE]

PMCID: PMC1414081

ReviewCritical determinants of metastasis.
Semin Cancer Biol. 2002 Apr; 12(2):89-96.

[Semin Cancer Biol. 2002]
ReviewMolecular targets in metastasis: lessons from genomic approaches.
Cancer Genomics Proteomics. 2007 May-Jun; 4(3):211-21.

[Cancer Genomics Proteomics. 2007]
A molecular signature of metastasis in primary solid tumors.
Nat Genet. 2003 Jan; 33(1):49-54. Epub 2002 Dec 9.

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ReviewMetastasis signatures: genes regulating tumor-microenvironment interactions predict metastatic behavior.
Cancer Metastasis Rev. 2008 Mar; 27(1):75-83.

[Cancer Metastasis Rev. 2008]
ReviewGrowth dominance of the metastatic cancer cell: cellular and molecular aspects.
Adv Cancer Res. 1990; 55:87-132.

[Adv Cancer Res. 1990]
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