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Ulysses - an application for the projection of molecular interactions across species.
Center for Genomics and Bioinformatics, Karolinska Institutet, 171 77 Stockholm, Sweden. danielle@cmmt.ubc.ca
We developed Ulysses as a user-oriented system that uses a process called Interolog Analysis for the parallel analysis and display of protein interactions detected in various species. Ulysses was designed to perform such Interolog Analysis by the projection of model organism interaction data onto homologous human proteins, and thus serves as an accelerator for the analysis of uncharacterized human proteins. The relevance of projections was assessed and validated against published reference collections. All source code is freely available, and the Ulysses system can be accessed via a web interface http://www.cisreg.ca/ulysses.
PMID: 16356269 [PubMed - indexed for MEDLINE]
PMCID: PMC1414088
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Cited by 8 PubMed Central articles
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Prediction of Protein-protein Interactions on the Basis of Evolutionary Conservation of Protein Functions.
Kotelnikova E, Kalinin A, Yuryev A, Maslov S.
Evol Bioinform Online. 2007 Aug 8; 3:197-206. Epub 2007 Aug 8.
[Evol Bioinform Online. 2007]
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POINeT: protein interactome with sub-network analysis and hub prioritization.
Lee SA, Chan CH, Chen TC, Yang CY, Huang KC, Tsai CH, Lai JM, Wang FS, Kao CY, Huang CY.
BMC Bioinformatics. 2009 Apr 21; 10:114. Epub 2009 Apr 21.
[BMC Bioinformatics. 2009]
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Ortholog-based protein-protein interaction prediction and its application to inter-species interactions.
Lee SA, Chan CH, Tsai CH, Lai JM, Wang FS, Kao CY, Huang CY.
BMC Bioinformatics. 2008 Dec 12; 9 Suppl 12:S11. Epub 2008 Dec 12.
[BMC Bioinformatics. 2008]
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