Can Fam Physician. 2005 Nov;51:1481-3.

Use of steroids for erythema multiforme in children.

Source

Hospital for Sick Children, Toronto, ON.

Abstract

QUESTION: I recently diagnosed an erythema multiforme rash in several patients, two of whom had the major variant, Stevens-Johnson syndrome. Should these patients be managed with corticosteroids? ANSWER: In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.

PMID:: 16353829; [PubMed - indexed for MEDLINE]
PMCID: PMC1479482

Free PMC Article

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

Glucocorticoids

LinkOut - more resources

Full Text Sources

Medical

Steroids - MedlinePlus Health Information

Supplemental Content

Related citations

[Erythema multiforme in children versus Stevens-Johnson syndrome]. [Wiad Lek. 2000]
[Erythema multiforme in children versus Stevens-Johnson syndrome].
Czubkowska I, Barszczak H, Koźniewska D, Wasaznik G. Wiad Lek. 2000; 53(1-2):43-8.
Analysis of the acute ophthalmic manifestations of the erythema multiforme/Stevens-Johnson syndrome/toxic epidermal necrolysis disease spectrum. [Ophthalmology. 1995]
Analysis of the acute ophthalmic manifestations of the erythema multiforme/Stevens-Johnson syndrome/toxic epidermal necrolysis disease spectrum.
Power WJ, Ghoraishi M, Merayo-Lloves J, Neves RA, Foster CS. Ophthalmology. 1995 Nov; 102(11):1669-76.
Erythema multiforme. [Dermatol Clin. 1985]
Erythema multiforme.
Huff JC. Dermatol Clin. 1985 Jan; 3(1):141-52.
Review Erythema multiforme due to Mycoplasma pneumoniae infection in two children. [Pediatr Dermatol. 2006]
Review Erythema multiforme due to Mycoplasma pneumoniae infection in two children.
Schalock PC, Dinulos JG, Pace N, Schwarzenberger K, Wenger JK. Pediatr Dermatol. 2006 Nov-Dec; 23(6):546-55.
Review Mycoplasma pneumoniae infection is associated with Stevens-Johnson syndrome, not erythema multiforme (von Hebra). [J Am Acad Dermatol. 1996]
Review Mycoplasma pneumoniae infection is associated with Stevens-Johnson syndrome, not erythema multiforme (von Hebra).
Tay YK, Huff JC, Weston WL. J Am Acad Dermatol. 1996 Nov; 35(5 Pt 1):757-60.

See reviews... See all...

Cited by 1 PubMed Central article

The role of systemic corticosteroid therapy in erythema multiforme major and stevens-johnson syndrome: a review of past and current opinions. [J Clin Aesthet Dermatol. 2009]
The role of systemic corticosteroid therapy in erythema multiforme major and stevens-johnson syndrome: a review of past and current opinions.
Michaels B. J Clin Aesthet Dermatol. 2009 Mar; 2(3):51-5.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Use of steroids for erythema multiforme in children.
Use of steroids for erythema multiforme in children.
Can Fam Physician. 2005 Nov ;51:1481-3.

PubMed
Erythema multiforme.
Erythema multiforme.
Am Fam Physician. 2006 Dec 1 ;74(11):1883-8.

PubMed
"Blue balls": A diagnostic consideration in testiculoscrotal pain in young adult...
"Blue balls": A diagnostic consideration in testiculoscrotal pain in young adults: A case report and discussion.
Pediatrics. 2000 Oct ;106(4):843.

PubMed
No effect of MMR withdrawal on the incidence of autism: a total population study...
No effect of MMR withdrawal on the incidence of autism: a total population study.
J Child Psychol Psychiatry. 2005 Jun ;46(6):572-9.

PubMed
Novel perspectives for progesterone in hormone replacement therapy, with special...
Novel perspectives for progesterone in hormone replacement therapy, with special reference to the nervous system.
Endocr Rev. 2007 Jun ;28(4):387-439. Epub 2007 Apr 12 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: