Mol Genet Metab. 2006 May;88(1):100-2. Epub 2005 Dec 15.

Cerebral 1H MR spectroscopy showing elevation of brain guanidinoacetate in argininosuccinate lyase deficiency.

Sijens PE, Reijngoud DJ, Soorani-Lunsing RJ, Oudkerk M, van Spronsen FJ.

Source

Department of Radiology, University Medical Centre Groningen and University of Groningen, Groningen, 9713 GZ, The Netherlands. p.e.sijens@rad.umcg.nl

Abstract

MR spectroscopy in a patient with argininosuccinate lyase deficiency revealed elevated cerebral guanidinoacetate signals, indicating that the phenomenon of increased levels of this compound in brain tissue is not limited to creatine deficiencies.

PMID:: 16343968; [PubMed - indexed for MEDLINE]

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