Biochim Biophys Acta. 1992 Jul 13;1122(1):57-62.

Characterization of aldehyde reductase of Sporobolomyces salmonicolor.

Kataoka M, Sakai H, Morikawa T, Katoh M, Miyoshi T, Shimizu S, Yamada H.

Source

Department of Agricultural Chemistry, Kyoto University, Japan.

Abstract

An NADPH-dependent aldehyde reductase (EC 1.1.1.2) isolated from Sporobolomyces salmonicolor AKU 4429 was further characterized. The enzyme also catalyzed the reductions of D-glucuronate, D-glucose, D-xylose and D-galactose at high concentrations. Km values for D-glucuronate and D-glucose are 345 and 4270 mM, respectively. Quercetin, dicoumarol and some SH-reagents inhibited the enzyme activity. NH2-terminal amino acid sequence analysis showed that the S. salmonicolor enzyme is partially the same as the aldo-keto reductase family proteins in primary protein structure.

PMID:: 1633196; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Supplemental Content

Save items

Related citations in PubMed

Cloning of the aldehyde reductase gene from a red yeast, Sporobolomyces salmonicolor, and characterization of the gene and its product. [Appl Environ Microbiol. 1996]
Cloning of the aldehyde reductase gene from a red yeast, Sporobolomyces salmonicolor, and characterization of the gene and its product.
Kita K, Matsuzaki K, Hashimoto T, Yanase H, Kato N, Chung MC, Kataoka M, Shimizu S. Appl Environ Microbiol. 1996 Jul; 62(7):2303-10.
Chiral alcohol synthesis with microbial carbonyl reductases in a water-organic solvent two-phase system. [Ann N Y Acad Sci. 1998]
Chiral alcohol synthesis with microbial carbonyl reductases in a water-organic solvent two-phase system.
Shimizu S, Kataoka M, Kita K. Ann N Y Acad Sci. 1998 Dec 13; 864:87-95.
Cloning, overexpression, and mutagenesis of the Sporobolomyces salmonicolor AKU4429 gene encoding a new aldehyde reductase, which catalyzes the stereoselective reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (S)-4-chloro-3-hydroxybutanoate. [Appl Environ Microbiol. 1999]
Cloning, overexpression, and mutagenesis of the Sporobolomyces salmonicolor AKU4429 gene encoding a new aldehyde reductase, which catalyzes the stereoselective reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (S)-4-chloro-3-hydroxybutanoate.
Kita K, Fukura T, Nakase KI, Okamoto K, Yanase H, Kataoka M, Shimizu S. Appl Environ Microbiol. 1999 Dec; 65(12):5207-11.
Review Catalytic mechanism and substrate selectivity of aldo-keto reductases: insights from structure-function studies of Candida tenuis xylose reductase. [IUBMB Life. 2006]
Review Catalytic mechanism and substrate selectivity of aldo-keto reductases: insights from structure-function studies of Candida tenuis xylose reductase.
Kratzer R, Wilson DK, Nidetzky B. IUBMB Life. 2006 Sep; 58(9):499-507.
Review All in the family: aldose reductase and closely related aldo-keto reductases. [Cell Mol Life Sci. 2004]
Review All in the family: aldose reductase and closely related aldo-keto reductases.
Petrash JM. Cell Mol Life Sci. 2004 Apr; 61(7-8):737-49.

See reviews... See all...

Cited by 6 PubMed Central articles

Molecular cloning and biochemical characterization of a novel erythrose reductase from Candida magnoliae JH110. [Microb Cell Fact. 2010]
Molecular cloning and biochemical characterization of a novel erythrose reductase from Candida magnoliae JH110.
Lee DH, Lee YJ, Ryu YW, Seo JH. Microb Cell Fact. 2010 Jun 8; 9:43. Epub 2010 Jun 8.
Purification and characterization of a novel alcohol dehydrogenase from Leifsonia sp. strain S749: a promising biocatalyst for an asymmetric hydrogen transfer bioreduction. [Appl Environ Microbiol. 2005]
Purification and characterization of a novel alcohol dehydrogenase from Leifsonia sp. strain S749: a promising biocatalyst for an asymmetric hydrogen transfer bioreduction.
Inoue K, Makino Y, Itoh N. Appl Environ Microbiol. 2005 Jul; 71(7):3633-41.
Cloning, overexpression, and mutagenesis of the Sporobolomyces salmonicolor AKU4429 gene encoding a new aldehyde reductase, which catalyzes the stereoselective reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (S)-4-chloro-3-hydroxybutanoate. [Appl Environ Microbiol. 1999]
Cloning, overexpression, and mutagenesis of the Sporobolomyces salmonicolor AKU4429 gene encoding a new aldehyde reductase, which catalyzes the stereoselective reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (S)-4-chloro-3-hydroxybutanoate.
Kita K, Fukura T, Nakase KI, Okamoto K, Yanase H, Kataoka M, Shimizu S. Appl Environ Microbiol. 1999 Dec; 65(12):5207-11.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
Protein
Protein translation features of primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Characterization of aldehyde reductase of Sporobolomyces salmonicolor.
Characterization of aldehyde reductase of Sporobolomyces salmonicolor.
Biochim Biophys Acta. 1992 Jul 13 ;1122(1):57-62.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Characterization of aldehyde reductase of Sporobolomyces salmonicolor.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Molecular Biology Databases

Research Materials

Miscellaneous

Supplemental Content

Save items

Related citations in PubMed

Cited by 6 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information