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Cell. 2005 Dec 2;123(5):769-72.

Can 1000 reviews be wrong? Actin, alpha-Catenin, and adherens junctions.

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  • 1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Abstract

Coupling between cell adhesion and the actin cytoskeleton is thought to require a stable link between the cadherin-catenin complex and actin that is mediated by alpha-catenin. In this issue of Cell, the Weis and Nelson groups call this static model into question, showing that alpha-catenin can directly regulate actin dynamics (Drees et al., 2005 and Yamada et al., 2005).

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PMID:
16325573
[PubMed - indexed for MEDLINE]
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