Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Immunol Lett. 2006 Feb 28;103(1):27-32. Epub 2005 Nov 21.

Essentials of biorecognition: the (strept)avidin-biotin system as a model for protein-protein and protein-ligand interaction.

Author information

  • 1Department of Biological Chemistry, The Weizmann Institute of Science, 76100 Rehovot, Israel. meir.wilchek@weizmann.ac.il

Abstract

Molecular recognition or biorecognition is as the heart of all biological interactions. These interactions are characterized by a collection of noncovalent bonds, namely ionic, hydrogen-bonding and hydrophobic interactions. In addition, shape complementarity appears to play a pivotal role in the process of biorecognition. In this review, we examine the versatile avidin-biotin complex as a model system for study of the biorecognition phenomenon with respect to protein-protein, protein-peptide, protein-ligand and protein-DNA interactions.

PMID:
16325268
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk