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Ethn Dis. 2005 Autumn;15(4 Suppl 6):S6-4-17.

Toward resolution of cardiovascular health disparities in African Americans: design and methods of the Jackson Heart Study.

Author information

  • 1School of Medicine and the Examination Center, Jackson Heart Study, University of Mississippi Medical Center, Jackson 39216-4505, USA. htaylor@medicine.umsmed.edu

Abstract

OBJECTIVE:

The design, overall methods, and major phenotypes for the all-African-American Jackson Heart Study (JHS) are detailed.

METHODS:

Participants were enrolled from the three counties that make up the Jackson, Mississippi metropolitan area. Relatives of selected participants were recruited to develop a large, nested family cohort. Participants provided extensive medical and social history, had an array of physical and biochemical measurements and diagnostic procedures, and provided genomic DNA.

RESULTS:

Data and biologic materials have been collected from 5302 adult African Americans, including 1499 members of 291 families. Participants have a high prevalence of diabetes, hypertension, obesity, and related disorders.

DISCUSSION:

The JHS dataset and biologic materials (serum, DNA, and cryopreserved cells) offer a valuable resource for the study of diseases that are of particular importance to African Americans.

PMID:
16320381
[PubMed - indexed for MEDLINE]
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