Design, synthesis and evaluation of near-infrared fluorescent pH indicators in a physiologically relevant range

Chem Commun (Camb). 2005 Dec 21:(47):5887-9. doi: 10.1039/b512315a. Epub 2005 Oct 20.

Abstract

Removal of a hydroxylsulfonylbutyl arm from indocyanine green dye produced a pH-sensitive near-infrared (NIR) fluorescent indicator that is useful at physiological range.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Fluorescent Dyes / chemical synthesis*
  • Fluorescent Dyes / chemistry*
  • Hydrogen-Ion Concentration
  • Indocyanine Green / chemistry
  • Infrared Rays
  • Molecular Structure

Substances

  • Fluorescent Dyes
  • Indocyanine Green