Phytochem Anal. 2005 Nov-Dec;16(6):463-9.

Analysis of macamides in samples of Maca (Lepidium meyenii) by HPLC-UV-MS/MS.

McCollom MM, Villinski JR, McPhail KL, Craker LE, Gafner S.

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Tom's of Maine, Kennebunk, ME 04043, USA.

Abstract

The macamides are a distinct class of secondary metabolites that have so far been found only in Lepidium meyenii Walp. (Maca). Using HPLC-UV-MS/MS, the main macamides have been identified as n-benzylhexadecanamide, n-benzyl-(9Z)-octadecenamide, n-benzyl-(9Z, 12Z)-octadecadienamide, n-benzyl-(9Z, 12Z, 15Z)-octadecatrienamide and n-benzyloctadecanamide. The identities of n-benzyl-(9Z)-octadecenamide and n-benzyl-(9Z, 12Z)-octadecadienamide were confirmed by comparison of chromatographic and spectral properties with synthetic analogues. Total macamides have been quantified by HPLC-UV in plant material from different vendors using n-benzylhexadecanamide as an external standard. The amount of macamides in the dried plant material ranged from 0.0016 to 0.0123%.

PMID:: 16315492; [PubMed - indexed for MEDLINE]

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